SCHEMBL11900436

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12490673	0.88	NPC1 (0.61)	ALDH1A1HPGDHSD17B10NPC1RAB9A
	SCHEMBL16861595	0.83	NPC1 (0.71)	ALDH1A1MGLLMEN1KMT2ANPC1
	SCHEMBL2349726	0.83	NPC1 (0.70)	ALDH1A1HSD17B10MEN1KMT2ANPC1
	SCHEMBL11900371	0.83	SRD5A2 (0.57)	ALDH1A1HPGDMEN1KMT2ANPC1
	SCHEMBL20134881	0.81	POLB (0.62)	ALDH1A1MGLLMEN1KMT2ANPC1
	SCHEMBL24232929	0.80	LOXL2 (0.47)	ALDH1A1HPGDALOX15MGLLHSD17B10
	SCHEMBL12733062	0.80	HPGD (0.53)	ALDH1A1HPGDALOX15MGLLHSD17B10
	SCHEMBL13944265	0.80	MEN1 (0.66)	ALDH1A1HSD17B10MEN1KMT2ANPC1
	Hydrochloric Acid SCHEMBL4193255	0.79	MEN1 (0.69)	ALDH1A1HSD17B10MEN1KMT2ANPC1
	SCHEMBL1707168	0.78	MEN1 (0.54)	ALDH1A1HPGDALOX15MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.