Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424632 | 0.86 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL11389506 | 0.83 | GABRA1 (0.61) | CCKBRCCKAR | |
| SCHEMBL11385919 | 0.81 | GABRA1 (0.61) | CCKBRCCKAR | |
| SCHEMBL30056423 | 0.80 | GABRA1 (0.72) | CCKBRCCKAR | |
| SCHEMBL1199478 | 0.80 | GABRA1 (0.72) | CCKBRCCKAR | |
| SCHEMBL7718314 | 0.80 | GABRA1 (0.72) | CCKBRCCKAR | |
| SCHEMBL3137800 | 0.80 | GABRA1 (0.72) | CCKBRCCKAR | |
| SCHEMBL30948956 | 0.79 | GABRA1 (0.57) | CCKBR | |
| SCHEMBL9525377 | 0.78 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9525370 | 0.78 | CCKBR (1.00) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202799-A1 | Condensed Azepine Derivatives As Bromodomain Inhibitors | GLAXOSMITHKLINE LLC | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202799-A1 | Condensed Azepine Derivatives As Bromodomain Inhibitors | BRD4, BRD3, BRD2 | CCKBR 363/4885CCKAR 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.