Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903208 | 1.00 | HTT (0.34) | HTTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11902903 | 0.85 | HTT (0.38) | HTTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11902300 | 0.83 | PDE4D (0.37) | PDE4APDE4BPDE4CPDE4DTSPO | |
| SCHEMBL11903209 | 0.82 | ALDH1A1 (0.42) | HTTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL12786061 | 0.82 | ALDH1A1 (0.42) | HTTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11903067 | 0.82 | HTT (0.38) | HTTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11902799 | 0.78 | ALDH1A1 (0.34) | KDM4EKMT2ANPC1MAPK1NPSR1 | |
| SCHEMBL11902803 | 0.78 | ALDH1A1 (0.34) | KDM4EKMT2ANPC1MAPK1NPSR1 | |
| SCHEMBL11902674 | 0.76 | ALDH1A1 (0.43) | KDM4EMEN1KMT2AMAPK1NPSR1 | |
| SCHEMBL11902676 | 0.76 | ALDH1A1 (0.43) | KDM4EMEN1KMT2AMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | HTT 216/4885KDM4E 3599/4885MEN1 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.