Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20377832 | 0.86 | AKR1C3 (0.54) | PARP10ALDH1A1NQO1TDP1TSHR | |
| SCHEMBL18725095 | 0.85 | PARP10 (0.61) | PARP10ALDH1A1NQO1PRSS1PRSS2 | |
| SCHEMBL10845631 | 0.83 | MMP9 (0.64) | TSHRLMNANPC1POLBMAPT | |
| SCHEMBL11903485 | 0.82 | FFAR1 (0.58) | ALDH1A1TSHR | |
| SCHEMBL4220063 | 0.81 | MAPT (0.45) | PARP10ACACBLMNAMAPT | |
| SCHEMBL2879870 | 0.79 | CA1 (0.53) | PARP10MEN1CYP1A2KMT2A | |
| SCHEMBL1354444 | 0.79 | CA1 (0.53) | PARP10MEN1CYP1A2KMT2A | |
| SCHEMBL1115061 | 0.79 | CA1 (0.53) | PARP10MEN1CYP1A2KMT2A | |
| SCHEMBL11080051 | 0.77 | PARP10 (0.56) | PARP10ALDH1A1NQO1PRSS1PRSS2 | |
| SCHEMBL20436808 | 0.77 | NQO1 (0.64) | PARP10ALDH1A1NQO1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844366-B2 | Sulfonamide hydroxamates | SYNTEX (U.S.A.) LLC (US) | 2005-01-18 | — | — | US | claimed |