Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 18/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903526 | 1.00 | ADRB2 (0.54) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11903502 | 1.00 | ADRB2 (0.54) | ADRB2ADRB3ADRB1 | |
| SCHEMBL524163 | 0.87 | ADRB2 (0.72) | ADRB2ADRB3ADRB1 | |
| SCHEMBL4240814 | 0.87 | ADRB2 (0.72) | ADRB2ADRB3ADRB1 | |
| SCHEMBL30480372 | 0.87 | ADRB2 (0.72) | ADRB2ADRB3ADRB1 | |
| SCHEMBL524162 | 0.87 | ADRB2 (0.72) | ADRB2ADRB3ADRB1 | |
| SCHEMBL12213641 | 0.81 | ADRB2 (0.61) | ADRB2ADRB3ADRB1 | |
| SCHEMBL5028852 | 0.73 | ADRB2 (0.62) | ADRB2ADRB3ADRB1 | |
| SCHEMBL2010699 | 0.73 | ADRB2 (0.62) | ADRB2ADRB3ADRB1 | |
| SCHEMBL523404 | 0.73 | ADRB2 (0.62) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242177-B2 | Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the β2 adrenergic receptor | ALMIRALL, S.A. (ES) | 2012-08-14 | — | — | US | disclosed |