Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.72 |
| ▸ | ADRB3 | P13945 | 19/20 | 0.72 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240814 | 1.00 | ADRB2 (0.72) | ADRB2ADRB3ADRB1 | |
| SCHEMBL524162 | 1.00 | ADRB2 (0.72) | ADRB2ADRB3ADRB1 | |
| SCHEMBL524163 | 1.00 | ADRB2 (0.72) | ADRB2ADRB3ADRB1 | |
| SCHEMBL12213641 | 0.92 | ADRB2 (0.61) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11903526 | 0.87 | ADRB2 (0.54) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11903502 | 0.87 | ADRB2 (0.54) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11903513 | 0.87 | ADRB2 (0.54) | ADRB2ADRB3ADRB1 | |
| SCHEMBL30510394 | 0.86 | ADRB2 (0.69) | ADRB2ADRB3ADRB1 | |
| SCHEMBL185382 | 0.86 | ADRB2 (0.69) | ADRB2ADRB3ADRB1 | |
| SCHEMBL28335500 | 0.86 | ADRB2 (0.69) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223294-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MEDIATED DISEASES | Vertex Pharmaceuticals Incorporated (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3436446-B1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2023-06-07 | — | — | EP | disclosed |