Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668474 | 0.84 | TPSAB1 (0.52) | HRH3LMNAMEN1KMT2AKDM4E | |
| SCHEMBL11903567 | 0.81 | POLB (0.43) | CA2CA12CA1CA9RAB9A | |
| SCHEMBL1668863 | 0.72 | TPSAB1 (0.51) | HRH3MEN1KMT2AKDM4E | |
| SCHEMBL3917814 | 0.71 | HRH3 (0.49) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL24564964 | 0.71 | PRMT6 (0.69) | CA2ALDH1A1POLBHRH3LMNA | |
| SCHEMBL5065800 | 0.69 | CA12 (0.80) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL12466576 | 0.69 | KDM4E (0.65) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL3921972 | 0.69 | GAA (0.52) | ALDH1A1HTTSMN1; SMN2POLBATM | |
| SCHEMBL3923607 | 0.68 | CA12 (0.60) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL10502128 | 0.68 | POLB (0.70) | CA2CA12CA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | claimed |