Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28499209 | 0.78 | MEN1 (0.51) | KMT2AMEN1 | |
| SCHEMBL907625 | 0.77 | MTNR1A (0.41) | KMT2AMEN1 | |
| SCHEMBL2723540 | 0.77 | KMT2A (0.68) | KMT2AMEN1ACHE | |
| SCHEMBL27526614 | 0.77 | KMT2A (0.68) | KMT2AMEN1ACHE | |
| SCHEMBL9314358 | 0.76 | KMT2A (0.66) | KMT2AMEN1ACHE | |
| Hydrochloric Acid SCHEMBL29289837 | 0.76 | KMT2A (0.66) | KMT2AMEN1ACHE | |
| SCHEMBL2721243 | 0.76 | KMT2A (0.66) | KMT2AMEN1ACHE | |
| SCHEMBL2030255 | 0.75 | THRB (0.49) | KMT2AMEN1ACHE | |
| SCHEMBL14889130 | 0.75 | GRIN2D (0.46) | — | |
| SCHEMBL3830344 | 0.74 | KMT2A (0.58) | KMT2AMEN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485595-A1 | COMBINATION THERAPY USING A BETA 3 ADRENERGIC RECEPTOR AGONIST AND AN ANTIMUSCARINIC AGENT | Merck Sharp & Dohme Corp. (US) | 2012-08-15 | — | — | EP | disclosed |