Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660727 | 0.88 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL1662897 | 0.74 | DPP4 (0.39) | CRHR1 | |
| SCHEMBL12731280 | 0.70 | NPC1 (0.46) | CRHR1 | |
| SCHEMBL12731279 | 0.68 | NPC1 (0.41) | CRHR1 | |
| SCHEMBL1659930 | 0.67 | NPC1 (0.38) | CRHR1 | |
| SCHEMBL1942048 | 0.66 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL12787456 | 0.65 | NPC1 (0.39) | CRHR1 | |
| SCHEMBL1922452 | 0.65 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL1660803 | 0.64 | LMNA (0.48) | — | |
| SCHEMBL11903817 | 0.64 | NPC1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487177-A1 | PYRAZOLOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2012-08-15 | — | — | EP | disclosed |