Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472848 | 0.88 | CXCR4 (0.39) | CXCR4P2RX7OPRL1 | |
| SCHEMBL4246586 | 0.88 | CXCR4 (0.34) | CXCR4P2RX7 | |
| SCHEMBL15387270 | 0.84 | CXCR4 (0.33) | CXCR4 | |
| SCHEMBL8301709 | 0.78 | CXCR4 (0.40) | CXCR4OPRL1 | |
| SCHEMBL2472129 | 0.76 | CXCR4 (0.41) | CXCR4OPRL1 | |
| SCHEMBL8306365 | 0.76 | CXCR4 (0.41) | CXCR4OPRL1 | |
| SCHEMBL2470469 | 0.75 | CXCR4 (0.38) | CXCR4OPRL1 | |
| SCHEMBL11983250 | 0.75 | CXCR4 (0.38) | CXCR4OPRL1 | |
| SCHEMBL2472333 | 0.75 | CXCR4 (0.38) | CXCR4OPRL1 | |
| SCHEMBL2472407 | 0.75 | CXCR4 (0.38) | CXCR4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615633-B1 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY | GENZYME CORP (US) | 2012-08-15 | — | — | EP | claimed |