Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 7/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033169 | 0.73 | HDAC2 (0.47) | HDAC2HDAC1HDAC3HDAC4HDAC8 | |
| SCHEMBL8678744 | 0.73 | HDAC2 (0.43) | HDAC2HDAC1HDAC3HDAC4HDAC8 | |
| SCHEMBL13479818 | 0.72 | POLB (0.54) | ALDH1A1SMN1; SMN2KMT2ARAB9AATM | |
| SCHEMBL28330132 | 0.72 | HDAC2 (0.60) | HDAC2HDAC1HDAC3HDAC4HDAC8 | |
| Cyclohexane Carboxamide SCHEMBL10499934 | 0.71 | HDAC2 (0.42) | HDAC2HDAC1HDAC3HDAC4HDAC8 | |
| SCHEMBL27753290 | 0.70 | RAB9A (0.56) | HDAC2HDAC1HDAC3ALDH1A1KMT2A | |
| SCHEMBL11015837 | 0.69 | HDAC4 (0.43) | HDAC2HDAC1HDAC3HDAC4HDAC8 | |
| SCHEMBL5515923 | 0.69 | — | — | |
| SCHEMBL13479779 | 0.69 | HDAC8 (0.52) | HDAC2HDAC1HDAC3HDAC8HDAC6 | |
| SCHEMBL15759686 | 0.68 | HDAC2 (0.48) | HDAC2HDAC1HDAC3HDAC4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975162-B1 | OXAZOLONE DERIVATIVE | SEIKAGAKU KOGYO CO LTD (JP) | 2012-08-15 | — | — | EP | disclosed |