Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15759686 | 0.94 | HDAC2 (0.48) | HDAC2HDAC8HDAC6HDAC4HDAC1 | |
| SCHEMBL9577685 | 0.92 | HDAC2 (0.50) | HDAC2HDAC8HDAC6HDAC4HDAC1 | |
| SCHEMBL6268542 | 0.86 | HDAC2 (0.52) | HDAC2HDAC8HDAC6HDAC4HDAC1 | |
| SCHEMBL11015837 | 0.79 | HDAC4 (0.43) | HDAC2HDAC8HDAC6HDAC4HDAC1 | |
| Cyclohexane Carboxamide SCHEMBL10499934 | 0.78 | HDAC2 (0.42) | HDAC2HDAC8HDAC6HDAC4HDAC1 | |
| SCHEMBL8678742 | 0.74 | HDAC2 (0.44) | HDAC2HDAC8HDAC6HDAC4HDAC1 | |
| SCHEMBL11904567 | 0.73 | HDAC2 (0.49) | HDAC2HDAC8HDAC6HDAC4HDAC1 | |
| SCHEMBL8678744 | 0.73 | HDAC2 (0.43) | HDAC2HDAC8HDAC6HDAC4HDAC1 | |
| SCHEMBL19743532 | 0.72 | RIPK1 (0.32) | HDAC2HDAC8HDAC6HDAC4HDAC1 | |
| SCHEMBL19743533 | 0.72 | RIPK1 (0.32) | HDAC2HDAC8HDAC6HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485061-B1 | Substituted cyclopentenyloxabicyclooctanes, cyclopentenyl-formylcyclohexenes, cyclopentenylhydroxymethyl cyclohexenes and camphonyl spirocyclooxaoctane-containing compositions, organoleptic uses thereof and process for preparing same | INT FLAVORS & FRAGRANCES INC (US) | 1996-01-03 | — | — | EP | claimed |