SCHEMBL11904662

SCHEMBL11904662

NC1C=CNC(=O)N1CO

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7065991 0.63
SCHEMBL198235 0.55 L3MBTL1 (0.76) L3MBTL1
SCHEMBL3728393 0.52
SCHEMBL1711289 0.52 L3MBTL1 (0.45) L3MBTL1
SCHEMBL12418938 0.52 L3MBTL1 (0.56) L3MBTL1
SCHEMBL11623973 0.51
SCHEMBL668722 0.51 L3MBTL1 (0.34) L3MBTL1
SCHEMBL811858 0.50 L3MBTL1 (0.33) L3MBTL1
SCHEMBL8600000 0.50 ITGB1 (0.37) L3MBTL1
SCHEMBL27353696 0.49

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2982755-A1 TREATMENT OF 'C TERMINUS OF HSP70-INTERACTING PROTEIN' (CHIP) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO CHIP CuRNA, Inc. (US) 2016-02-10 EP disclosed
EP-2153843-B1 Compositions and methods for the diagnosis and treatment of tumor GENENTECH INC (US) 2012-08-15 EP disclosed
CN-101132795-A Compounds useful in the treatment of HIV MEDIVIR AB (SE) 2008-02-27 CN disclosed