Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10109356 | 0.71 | KDM4E (0.48) | NPC1RAB9ALMNACYP1A2CYP2C9 | |
| SCHEMBL317927 | 0.71 | KDM4E (0.48) | NPC1RAB9ALMNACYP1A2CYP2C9 | |
| SCHEMBL25977061 | 0.70 | SLC6A2 (0.45) | NPC1RAB9ALMNASMN1; SMN2SLC6A3 | |
| SCHEMBL13229416 | 0.70 | BACE1 (0.42) | NPC1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL3692359 | 0.70 | BACE1 (0.42) | NPC1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4805229 | 0.69 | KMT2A (0.75) | NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13859676 | 0.69 | LMNA (0.68) | NPC1RAB9ALMNACYP1A2CYP2C9 | |
| SCHEMBL16604902 | 0.69 | LMNA (0.68) | NPC1RAB9ALMNACYP1A2CYP2C9 | |
| SCHEMBL14817293 | 0.69 | LMNA (0.68) | NPC1RAB9ALMNACYP1A2CYP2C9 | |
| SCHEMBL8585264 | 0.68 | KMT2A (0.72) | NPC1RAB9ASMN1; SMN2MAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2290651-B1 | Compositions, optical data storage media and methods for using the optical data storage media | GEN ELECTRIC (US) | 2012-10-10 | — | — | EP | claimed |
| EP-2290408-B1 | Compositions, optical data storage media and methods for using the optical data storage media | GEN ELECTRIC (US) | 2012-08-15 | — | — | EP | claimed |