Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL10944368 | 0.96 | TSHR (0.44) | TSHRHCAR2ALDH1A1HSD17B10HPGD | |
| SCHEMBL9161907 | 0.86 | TSHR (0.42) | TSHRHCAR2TP53 | |
| Acrylic Acid Methyl Ester SCHEMBL4640900 | 0.86 | HCAR2 (0.54) | TSHRHCAR2ALDH1A1HSD17B10HPGD | |
| Acrylic Acid Methyl Ester SCHEMBL8380741 | 0.85 | HCAR2 (0.49) | TSHRHCAR2ALDH1A1HSD17B10HPGD | |
| SCHEMBL2778233 | 0.83 | TSHR (0.58) | TSHRHCAR2ALDH1A1HSD17B10HPGD | |
| SCHEMBL5859055 | 0.83 | TSHR (0.58) | TSHRHCAR2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11513248 | 0.82 | TSHR (0.49) | TSHRHCAR2ALDH1A1HSD17B10HPGD | |
| Monomethyl Fumarate SCHEMBL28099233 | 0.81 | TSHR (0.63) | TSHRHCAR2ALDH1A1HSD17B10HPGD | |
| Acrylic Acid Ethyl Ester SCHEMBL3421934 | 0.80 | TSHR (0.54) | TSHRHCAR2ALDH1A1HSD17B10HPGD | |
| Acrylic Acid Methyl Ester SCHEMBL8910788 | 0.80 | HCAR2 (0.40) | TSHRHCAR2ALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120205030-A1 | SPONTANEOUSLY ROLLING ADHESIVE SHEET AND METHOD OF MANUFACTURING CUT PIECE | NITTO DENKO CORPORATION (JP) | 2012-08-16 | — | — | US | disclosed |