Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441140 | 1.00 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL11929885 | 0.95 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL715845 | 0.92 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL385140 | 0.92 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL460819 | 0.92 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL716534 | 0.92 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL462943 | 0.92 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL10130128 | 0.90 | AVPR2 (0.69) | AVPR2AVPR1A | |
| SCHEMBL718656 | 0.90 | AVPR2 (0.74) | AVPR2AVPR1A | |
| SCHEMBL717387 | 0.90 | AVPR2 (0.74) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208852-A1 | Heterocyclic-substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208852-A1 | Heterocyclic-substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | AADAC, NAT1, TNNI3 | AVPR2 1651/4885AVPR1A 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.