Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 20/20 | 0.73 |
| ▸ | AVPR1A | P37288 | 20/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | OXTR | P30559 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462943 | 1.00 | AVPR2 (0.73) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL715845 | 1.00 | AVPR2 (0.73) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL716534 | 1.00 | AVPR2 (0.73) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL385140 | 1.00 | AVPR2 (0.73) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL10130128 | 0.93 | AVPR2 (0.69) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL717387 | 0.93 | AVPR2 (0.74) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL718656 | 0.93 | AVPR2 (0.74) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL1441140 | 0.92 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL11907041 | 0.92 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL6915489 | 0.92 | AVPR2 (0.71) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408754-A1 | Triazole derivatives as vasopressin-receptor inhibitors for treating cardiac insufficiency | Bayer Pharma Aktiengesellschaft (DE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105750-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN-RECEPTOR INHIBITORS FOR TREATING CARDIAC INSUFFICIENCY | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |