SCHEMBL11907490

SCHEMBL11907490

COC(=O)C(CCCCNC(=O)COCCOCC(=O)OCc1ccccc1)NC(=O)COCCOCC(=O)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 8/20 0.52
SIRT1 Q96EB6 6/20 0.52
SIRT3 Q9NTG7 3/20 0.52
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
FOLH1 Q04609 2/20 0.45
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11925972 1.00 SIRT2 (0.52) SIRT2SIRT1SIRT3CA1CA2
SCHEMBL11907039 0.96 SIRT2 (0.53) SIRT2SIRT1SIRT3CA1CA2
SCHEMBL11925819 0.96 SIRT2 (0.53) SIRT2SIRT1SIRT3CA1CA2
SCHEMBL4905245 0.90 SIRT2 (0.51) SIRT2SIRT1SIRT3CA1CA2
SCHEMBL4896764 0.89 SIRT2 (0.54) SIRT2SIRT1SIRT3CA1CA2
SCHEMBL16846627 0.89 SIRT2 (0.49) SIRT2SIRT1SIRT3CA1CA2
SCHEMBL11907491 0.83 SIRT2 (0.49) SIRT2SIRT1SIRT3CA1CA2
SCHEMBL31235832 0.81 FOLH1 (0.49) SIRT2SIRT1MEN1ALDH1A1HPGD
SCHEMBL11925975 0.81 GLP1R (0.53) SIRT2SIRT1SIRT3CA1CA2
SCHEMBL25932961 0.81 SIRT2 (0.59) SIRT2SIRT1SIRT3FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-06-23 US disclosed
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-06-23 US disclosed
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2020-05-28 US disclosed
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-02-04 US disclosed
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-02-04 US disclosed
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 US disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 US disclosed
US-9012677-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-04-21 US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 US disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 US disclosed
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2012-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM SLC7A1, SLC3A2, BCAT2 SIRT2 4317/4885SIRT1 4492/4885SIRT3 4320/4885
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 SIRT2 4480/4885SIRT1 4644/4885SIRT3 4525/4885
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 SIRT2 4480/4885SIRT1 4644/4885SIRT3 4525/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 SIRT2 4480/4885SIRT1 4644/4885SIRT3 4525/4885
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 SIRT2 4480/4885SIRT1 4644/4885SIRT3 4525/4885
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 SIRT2 4480/4885SIRT1 4644/4885SIRT3 4525/4885
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 SIRT2 4480/4885SIRT1 4644/4885SIRT3 4525/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 SIRT2 4480/4885SIRT1 4644/4885SIRT3 4525/4885
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 SIRT2 4480/4885SIRT1 4644/4885SIRT3 4525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.