Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11909122 | 1.00 | BRD4 (0.61) | BRD4HRH3KDM4EHSD17B10 | |
| SCHEMBL10104 | 0.90 | BRD4 (0.59) | BRD4 | |
| SCHEMBL10103 | 0.90 | BRD4 (0.59) | BRD4 | |
| SCHEMBL12764531 | 0.82 | BRD4 (0.52) | BRD4 | |
| SCHEMBL11197 | 0.81 | BRD4 (0.51) | BRD4 | |
| SCHEMBL11198 | 0.81 | BRD4 (0.51) | BRD4 | |
| SCHEMBL22259585 | 0.81 | BRD4 (0.51) | BRD4 | |
| SCHEMBL10379899 | 0.79 | ALDH1A1 (0.53) | BRD4HSD17B10 | |
| SCHEMBL15135545 | 0.78 | BRD4 (0.38) | BRD4KDM4E | |
| SCHEMBL15135544 | 0.78 | BRD4 (0.38) | BRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | FASN, FADS1, FADS2 | BRD4 277/4885HRH3 4184/4885KDM4E 1624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.