Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.48 |
| ▸ | LIPC | P11150 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11909231 | 1.00 | AKR1B1 (0.48) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11909530 | 0.92 | STAT3 (0.56) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11909527 | 0.92 | STAT3 (0.56) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7209 | 0.90 | STAT3 (0.45) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7207 | 0.90 | STAT3 (0.45) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11909680 | 0.86 | FAAH (0.44) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11909682 | 0.86 | FAAH (0.44) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11909744 | 0.84 | KAT2B (0.45) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11909741 | 0.84 | KAT2B (0.45) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11909942 | 0.84 | MAPK1 (0.42) | MEN1KMT2AMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | FASN, FADS1, FADS2 | AKR1B1 432/4885AKR1C4 767/4885AKR1C3 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.