SCHEMBL11909243

SCHEMBL11909243

O=C(CCl)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.68
▸ MEN1 O00255 1/20 0.68
▸ KMT2A Q03164 1/20 0.68
▸ ACE P12821 4/20 0.67
▸ ITGB2 P05107 7/20 0.66
▸ ICAM1 P05362 7/20 0.66
▸ ITGAL P20701 7/20 0.66
▸ ERAP2 Q6P179 2/20 0.65
▸ P2RY14 Q15391 1/20 0.64
▸ TP53 P04637 1/20 0.64
▸ POLB P06746 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194439 1.00 ALOX15 (0.68) ALOX15MEN1KMT2AACEITGB2
SCHEMBL3194433 1.00 ALOX15 (0.68) ALOX15MEN1KMT2AACEITGB2
SCHEMBL31267215 1.00 ALOX15 (0.68) ALOX15MEN1KMT2AACEITGB2
SCHEMBL29987387 0.88 ALOX15 (0.70) ALOX15MEN1KMT2AACEITGB2
SCHEMBL6313468 0.88 ALOX15 (0.70) ALOX15ACEITGB2ICAM1ITGAL
SCHEMBL30936746 0.88 ALOX15 (0.70) ALOX15MEN1KMT2AACEITGB2
SCHEMBL3728145 0.88 ALOX15 (0.70) ALOX15MEN1KMT2AACEITGB2
SCHEMBL13278205 0.88 ALOX15 (0.70) ALOX15MEN1KMT2AACEITGB2
SCHEMBL1994982 0.88 ALOX15 (0.70) ALOX15MEN1KMT2AACEITGB2
SCHEMBL1994981 0.88 ALOX15 (0.70) ALOX15MEN1KMT2AACEITGB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 — — EP disclosed
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC (JP) 2026-04-09 — — US disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 — — WO disclosed
EP-4594337-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF Rayzebio, Inc. (US) 2025-08-06 — — EP disclosed
EP-4594336-A2 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PeptiDream Inc. (JP) 2025-08-06 — — EP disclosed
WO-2025084336-A1 MOLECULE CAPABLE OF SIMULTANEOUSLY BINDING TO AAV CAPSID AND TARGET RECEPTOR 国立大学法人大阪大学 2025-04-24 — — WO disclosed
WO-2024254339-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2024-12-12 — — WO disclosed
US-11975040-B2 Plexin binding regulator THE UNIVERSITY OF TOKYO (JP) 2024-05-07 — — US disclosed
US-11970694-B2 Rapid display method in translational synthesis of peptide PEPTIDREAM INC. (JP) 2024-04-30 — — US disclosed
WO-2024073622-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2024-04-04 — — WO disclosed
US-20160209421-A1 Macrocyclic Peptide, Method for Producing Same, and Screening Method Using Macrocyclic Peptide Library THE UNIVERSITY OF TOKYO (JP) 2016-07-21 — — US disclosed
EP-3040417-A1 MACROCYCLIC PEPTIDE, METHOD FOR PRODUCING SAME, AND SCREENING METHOD USING MACROCYCLIC PEPTIDE LIBRARY The University of Tokyo (JP) 2016-07-06 — — EP disclosed
EP-2492344-B1 RAPID DISPLAY METHOD IN TRANSLATIONAL SYNTHESIS OF PEPTIDE PEPTIDREAM INC (JP) 2016-04-06 — — EP disclosed
US-20150299258-A1 Peptide for Inhibiting Vascular Endothelial Growth Factor Receptor THE UNIVERSITY OF TOKYO (JP) 2015-10-22 — — US disclosed
EP-2894161-A1 PEPTIDE FOR INHIBITING VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR The University of Tokyo (JP) 2015-07-15 — — EP disclosed
EP-2615455-A1 TRANSLATION AND CONSTRUCTION OF NON-STANDARD PEPTIDE COMPOUND LIBRARY CONTAINING N-METHYL AMINO ACIDS AND OTHER NON-STANDARD AMINO ACIDS, AND METHOD FOR SEARCHING FOR ACTIVE SPECIES The University of Tokyo (JP) 2013-07-17 — — EP disclosed
US-20130178394-A1 METHOD FOR CONSTRUCTING LIBRARIES OF NON-STANDARD PEPTIDE COMPOUNDS COMPRISING N-METHYL AMINO ACIDS AND OTHER SPECIAL (NON-STANDARD) AMINO ACIDS AND METHOD FOR SEARCHING AND IDENTIFYING ACTIVE SPECIES THE UNIVERSITY OF TOKYO (JP) 2013-07-11 — — US disclosed
EP-2492344-A9 RAPID DISPLAY METHOD IN TRANSLATIONAL SYNTHESIS OF PEPTIDE PeptiDream Inc. (JP) 2013-02-20 — — EP disclosed
EP-2492344-A1 RAPID DISPLAY METHOD IN TRANSLATIONAL SYNTHESIS OF PEPTIDE PeptiDream Inc. (JP) 2012-08-29 — — EP disclosed
US-20120208720-A1 RAPID DISPLAY METHOD IN TRANSLATIONAL SYNTHESIS OF PEPTIDE PEPTIDREAM INC. (JP) 2012-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299258-A1 Peptide for Inhibiting Vascular Endothelial Growth Factor Receptor KDR, FLT4, TEK ALOX15 3979/4885MEN1 2546/4885KMT2A 3237/4885
US-20160209421-A1 Macrocyclic Peptide, Method for Producing Same, and Screening Method Using Macrocyclic Peptide Library VIP, SLC7A1, PITRM1 ALOX15 2904/4885MEN1 429/4885KMT2A 4274/4885
US-11975040-B2 Plexin binding regulator TEK, SERBP1, LRRFIP1 ALOX15 4298/4885MEN1 816/4885KMT2A 4095/4885
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME EPHA2, EPHA1, EPHB1 ALOX15 4691/4885MEN1 1816/4885KMT2A 748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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