Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | FLT3 | P36888 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10211456 | 0.90 | MAPT (0.46) | ALDH1A1KDM4ESMN1; SMN2RAB9APOLB | |
| SCHEMBL11911082 | 0.88 | MAPT (0.40) | ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL4333103 | 0.70 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2ASMN1; SMN2POLB | |
| SCHEMBL4323463 | 0.70 | KDM4E (0.58) | ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10210980 | 0.69 | TTK (0.39) | ALDH1A1KDM4EFLT3KMT2ASMN1; SMN2 | |
| SCHEMBL11910992 | 0.67 | MAPT (0.46) | ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL14564459 | 0.64 | TDP1 (0.47) | ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL2743133 | 0.64 | KDM4E (0.54) | ALDH1A1KDM4EKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL17868539 | 0.64 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10209898 | 0.64 | MAPT (0.44) | ALDH1A1KDM4ESMN1; SMN2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120195857-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120195857-A1 | Hepatitis C Virus Inhibitors | HAVCR2, PYGL, HCCS | ALDH1A1 1144/4885KDM4E 3857/4885FLT3 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.