SCHEMBL11912138

SCHEMBL11912138

O=C(Nc1cccc(Oc2cccc(Oc3cccc(N4C(=O)c5ccccc5C4=O)c3)c2)c1)c1ccc2c(c1)C(=O)N(c1cccc(Oc3cccc(Oc4cccc(N5C(=O)c6ccccc6C5=O)c4)c3)c1)C2=O

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.63
▸ TDP1 Q9NUW8 1/20 0.63
▸ RAB9A P51151 1/20 0.60
▸ ALDH1A1 P00352 2/20 0.60
▸ CTDSP1 Q9GZU7 2/20 0.60
▸ MEN1 O00255 4/20 0.56
▸ KMT2A Q03164 4/20 0.56
▸ ENPP2 Q13822 1/20 0.56
▸ GAA P10253 1/20 0.53
▸ CA12 O43570 1/20 0.53
▸ CA7 P43166 1/20 0.53
▸ PSMD14 O00487 1/20 0.53
▸ BLM P54132 1/20 0.53
▸ PLEC Q15149 1/20 0.53
▸ LPAR1 Q92633 1/20 0.53
▸ LPAR5 Q9H1C0 1/20 0.53
▸ LPAR3 Q9UBY5 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12761193 0.95 ALDH1A1 (0.62) POLBTDP1RAB9AALDH1A1CTDSP1
SCHEMBL15614027 0.82 MEN1 (0.70) POLBRAB9AALDH1A1CTDSP1MEN1
SCHEMBL14338938 0.81 RAB9A (0.73) POLBTDP1RAB9AALDH1A1CTDSP1
SCHEMBL9806710 0.81 RAB9A (0.65) POLBTDP1RAB9AALDH1A1CTDSP1
SCHEMBL9806704 0.80 ALDH1A1 (0.54) POLBTDP1RAB9AALDH1A1CTDSP1
SCHEMBL7593119 0.80 MEN1 (0.58) POLBTDP1RAB9AALDH1A1CTDSP1
SCHEMBL29728136 0.80 RAB9A (0.64) POLBTDP1RAB9AALDH1A1CTDSP1
SCHEMBL12111950 0.80 FFAR1 (0.59) POLBTDP1RAB9AALDH1A1MEN1
SCHEMBL9458368 0.79 HSD17B10 (0.76) POLBTDP1RAB9AALDH1A1CTDSP1
SCHEMBL15614028 0.79 POLB (0.69) POLBTDP1RAB9ACTDSP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236669-B2 High-temperature spin-on temporary bonding compositions BREWER SCIENCE INC. (US) 2012-08-07 — — US disclosed
US-7935780-B2 High-temperature spin-on temporary bonding compositions BREWER SCIENCE INC. (US) 2011-05-03 — — US disclosed
US-20090038750-A1 HIGH-TEMPERATURE SPIN-ON TEMPORARY BONDING COMPOSITIONS BREWER SCIENCE INC. 2009-02-12 — — US disclosed
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