Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621520 | 0.76 | MGLL (0.44) | LMNAALDH1A1PTGS1PTGS2MGLL | |
| SCHEMBL12094816 | 0.75 | MGLL (0.39) | LMNAALDH1A1PTGS1PTGS2MGLL | |
| SCHEMBL23673418 | 0.73 | MGLL (0.42) | LMNAALDH1A1PTGS1PTGS2MGLL | |
| SCHEMBL1691881 | 0.72 | ALDH1A1 (0.39) | ALDH1A1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL5908019 | 0.72 | MGLL (0.42) | LMNAALDH1A1PTGS1PTGS2MGLL | |
| SCHEMBL4277991 | 0.72 | MGLL (0.42) | LMNAALDH1A1PTGS1PTGS2MGLL | |
| SCHEMBL2362621 | 0.72 | MGLL (0.42) | LMNAALDH1A1PTGS1PTGS2MGLL | |
| SCHEMBL43970 | 0.71 | PTPN1 (0.42) | ALDH1A1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL24153641 | 0.71 | MGLL (0.45) | LMNAALDH1A1PTGS1PTGS2MGLL | |
| SCHEMBL4308441 | 0.71 | MGLL (0.45) | LMNAALDH1A1PTGS1PTGS2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232251-B2 | Compounds for delivery of therapeutic and imaging moieties to nerve cells | MANZANITA PHARMACEUTICALS, INC. (US) | 2012-07-31 | — | — | US | disclosed |
| US-20090286732-A1 | COMPOUNDS FOR DELIVERY OF THERAPEUTIC AND IMAGING MOIETIES TO NERVE CELLS | MANZANITA PHARMACEUTICALS, INC. | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286732-A1 | COMPOUNDS FOR DELIVERY OF THERAPEUTIC AND IMAGING MOIETIES TO NERVE CELLS | CLTB, NMBR, L1CAM | PLA2G2C 1804/4885LMNA 396/4885USP2 4646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.