SCHEMBL119132

SCHEMBL119132

COc1ccc(C(Br)c2ccc(OC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 1/20 0.58
CA14 Q9ULX7 1/20 0.58
TDP1 Q9NUW8 4/20 0.52
ALDH1A1 P00352 4/20 0.52
MAPK1 P28482 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
TSHR P16473 1/20 0.52
SLC2A1 P11166 1/20 0.48
ACHE P22303 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
GAA P10253 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL871495 0.91 ACP3 (0.56) CA1CA2CA7CA9CA12
SCHEMBL15087401 0.89 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL9425364 0.84 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL677832 0.82 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL11442189 0.81 APP (0.55) TDP1ALDH1A1MAPK1L3MBTL1CYP1A2
SCHEMBL28083383 0.80 ALDH1A1 (0.54) CA1CA2CA7CA9CA12
SCHEMBL1295194 0.80 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL27668587 0.80 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL7188669 0.79 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL19077747 0.78 CA1 (0.65) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4691558-A2 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS University Court of The University of Dundee (GB) 2026-02-11 EP disclosed
US-20250295789-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) 2025-09-25 US disclosed
EP-2857018-B1 Treatment or prophylaxis of proliferative conditions UNIV COURT OF THE UNIV OF DUNDEE (GB) 2025-09-03 EP disclosed
US-20220031852-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) 2022-02-03 US disclosed
US-20200360521-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) 2020-11-19 US disclosed
US-9919060-B2 Treatment or prophylaxis of proliferative conditions UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) 2018-03-20 US disclosed
US-20170368188-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) 2017-12-28 US disclosed
EP-2857018-A1 Treatment or prophylaxis of proliferative conditions University Court of The University of Dundee (GB) 2015-04-08 EP disclosed
US-20150011512-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) 2015-01-08 US disclosed
US-20120302748-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) 2012-11-29 US disclosed
US-5578415-A THIN FILM WITH LUSTER LAYER COMPRISING HYDROPHOBIC BINDER, METALLIC PARTICLES AND A TRANSPARENT PROTECTIVE FILM; LASER RECORDING, READING ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1996-11-26 US disclosed
EP-0361204-B1 Optical recording materials, method for preparing the same and optical cards having the same ASAHI CHEMICAL IND (JP) 1994-11-30 EP disclosed
EP-0361204-A2 Optical recording materials, method for preparing the same and optical cards having the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-04-04 EP disclosed
US-4335957-A Image forming method and apparatus therefor ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-06-22 US disclosed
US-4327176-A IMPACT RESISTANT ACRYLIC ESTER RESIN BINDER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-04-27 US disclosed
US-4325629-A Image forming method and apparatus therefor ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-04-20 US disclosed
US-4287295-A Image forming method and apparatus therefor ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-09-01 US disclosed
US-4268626-A Dry image forming material ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-05-19 US disclosed
US-4227799-A Image forming apparatus ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-10-14 US disclosed
US-4188226-A OXIDIZER, REDUCER, HALOGENATED CARBOCYCLIC COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200360521-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS CYP1B1, UGT1A1, CYP1A1 CA1 3263/4885CA2 2188/4885CA7 2835/4885
US-20120302748-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS BRCA1, CYP1B1, UGT1A1 CA1 4007/4885CA2 3157/4885CA7 3203/4885
US-20220031852-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS CYP1B1, UGT1A1, CYP1A1 CA1 3263/4885CA2 2188/4885CA7 2835/4885
US-20250295789-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS CYP1B1, BRCA1, UGT1A1 CA1 3527/4885CA2 2213/4885CA7 2831/4885
US-20170368188-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS CYP1B1, UGT1A1, CYP1A1 CA1 3344/4885CA2 2402/4885CA7 2285/4885
US-20150011512-A1 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS CYP1B1, UGT1A1, CYP1A1 CA1 3263/4885CA2 2188/4885CA7 2835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.