Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653854 | 0.86 | GCGR (0.37) | KDM4EPKMRCE1PDE4DPDE4B | |
| SCHEMBL11903008 | 0.81 | TSHR (0.43) | KDM4EPKMALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11902934 | 0.79 | TRPV1 (0.39) | KDM4EPKMRCE1PDE4DPDE4B | |
| SCHEMBL11903055 | 0.79 | HTT (0.42) | KDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL11903226 | 0.77 | HDAC1 (0.39) | KDM4EPDE4DPDE4BALDH1A1SMN1; SMN2 | |
| SCHEMBL11902630 | 0.76 | GRM2 (0.37) | PDE4DPDE4BPDE4APDE4CGRIN2B | |
| SCHEMBL11903405 | 0.76 | PDE4D (0.37) | PDE4DPDE4BPDE4APDE4CGRIN2B | |
| SCHEMBL1654710 | 0.74 | RHEB (0.40) | KDM4EPKMRCE1PDE4DPDE4B | |
| SCHEMBL11902528 | 0.74 | ABL1 (0.39) | KDM4EPKMRCE1PDE4DPDE4B | |
| SCHEMBL11903049 | 0.74 | GAA (0.41) | KDM4EALDH1A1SMN1; SMN2HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | GABRA2 954/4885GABRB2 544/4885KDM4E 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.