Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11913403 | 0.86 | GABRA2 (0.38) | GCGRPDE4DGRIN2BCYP1A2KDM4E | |
| SCHEMBL11903008 | 0.83 | TSHR (0.43) | KDM4EHPGDPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL11903055 | 0.81 | HTT (0.42) | KDM4EPPARDPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL11902957 | 0.78 | NOTUM (0.40) | CYP1A2PPARDPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL11902760 | 0.77 | NOTUM (0.39) | PDE4DGRIN2BPDE4BPDE4APDE4C | |
| SCHEMBL11903226 | 0.76 | HDAC1 (0.39) | GCGRPDE4DCYP1A2KDM4EPDE4B | |
| SCHEMBL11902934 | 0.74 | TRPV1 (0.39) | PDE4DCYP1A2KDM4EPDE4BPDE4A | |
| SCHEMBL11902325 | 0.74 | ALDH1A1 (0.40) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11902630 | 0.74 | GRM2 (0.37) | GCGRPDE4DGRIN2BCYP1A2PDE4B | |
| SCHEMBL1654751 | 0.74 | MAPK8 (0.41) | PDE4DCYP1A2KDM4EHPGDPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488518-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| CN-102574849-A | Herbicidal compounds | SYNGENTA LTD | 2012-07-11 | — | — | CN | disclosed |
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | GCGR 2802/4885PDE4D 3019/4885GRIN2B 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.