Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 2/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191018 | 0.95 | SLC22A12 (0.55) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 | |
| Bromide SCHEMBL1191225 | 0.94 | SLC22A12 (0.54) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 | |
| SCHEMBL1191479 | 0.92 | SLC22A12 (0.61) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 | |
| SCHEMBL1191290 | 0.90 | SLC22A12 (0.57) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 | |
| SCHEMBL1191174 | 0.89 | SLC22A12 (0.59) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 | |
| SCHEMBL1191676 | 0.86 | SLC22A12 (0.67) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 | |
| Bromide SCHEMBL1190540 | 0.85 | SLC22A12 (0.65) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 | |
| SCHEMBL1191389 | 0.84 | GPBAR1 (0.47) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 | |
| SCHEMBL1190479 | 0.84 | SLC22A12 (0.63) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 | |
| SCHEMBL1191393 | 0.83 | SLC22A12 (0.50) | SLC22A12SLC22A6SLC22A8POLBGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266989-A2 | HETEROCYCLIC DERIVATIVES | C&c Research Laboratories (KR) | 2010-12-29 | — | — | EP | claimed |
| US-8394792-B2 | Heterocyclic derivatives | C&C RESEARCH LABORATORIES (KR) | 2013-03-12 | — | — | US | disclosed |
| US-20110028467-A1 | HETEROCYCLIC DERIVATIVES | C&C RESEARCH LABORATORIES (KR) | 2011-02-03 | — | — | US | disclosed |
| EP-2266989-A2 | HETEROCYCLIC DERIVATIVES | C&c Research Laboratories (KR) | 2010-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028467-A1 | HETEROCYCLIC DERIVATIVES | XDH, NUDT1, UGDH | SLC22A12 692/4885SLC22A6 625/4885SLC22A8 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.