Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11913988 | 0.88 | MEN1 (0.39) | ABCB1KLK5 | |
| SCHEMBL11913986 | 0.85 | ABCB1 (0.42) | ABCB1 | |
| SCHEMBL10277330 | 0.82 | MEN1 (0.40) | ABCB1 | |
| SCHEMBL11913983 | 0.79 | ABCB1 (0.48) | ABCB1 | |
| SCHEMBL10277143 | 0.78 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL11918305 | 0.75 | ABCB1 (0.42) | ABCB1 | |
| SCHEMBL1666846 | 0.69 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL11913957 | 0.69 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL1669812 | 0.63 | ABCB1 (0.74) | ABCB1 | |
| SCHEMBL22649442 | 0.61 | KLK5 (0.54) | KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202756-A1 | USE OF PRODRUGS TO AVOID GI MEDIATED ADVERSE EVENTS | FRANKLIN RICHARD (GB) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202756-A1 | USE OF PRODRUGS TO AVOID GI MEDIATED ADVERSE EVENTS | OPRM1, UGT1A6, UGT1A4 | ABCB1 75/4885KLK5 3147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.