Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11914391 | 0.86 | ERN1 (0.39) | KDM1ATGFBR1ERN1PTGER2HDAC2 | |
| SCHEMBL11914285 | 0.80 | ERN1 (0.41) | KDM1ATGFBR1ERN1PTGER2HDAC2 | |
| SCHEMBL11914294 | 0.77 | ERN1 (0.39) | KDM1ATGFBR1ERN1PTGER2HDAC2 | |
| SCHEMBL16547062 | 0.73 | ALOX5 (0.45) | — | |
| SCHEMBL11914323 | 0.72 | CCR1 (0.41) | CYP11B1AVPR2AVPR1A | |
| SCHEMBL1102909 | 0.72 | PDK2 (0.36) | — | |
| SCHEMBL16547006 | 0.71 | ENPP1 (0.36) | AVPR2AVPR1AACVR1 | |
| SCHEMBL16546974 | 0.71 | BACE1 (0.40) | AVPR2AVPR1A | |
| SCHEMBL16547042 | 0.71 | COMT (0.33) | — | |
| SCHEMBL16547071 | 0.71 | ALOX5 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241763-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-08-14 | — | — | US | disclosed |
| US-8241763-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20090261717-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
| US-20090261717-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090261717-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, SLC26A3, SLCO4C1 | KDM1A 3601/4885TGFBR1 4056/4885ERN1 2386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.