Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA7 | P43166 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176957 | 0.80 | CA12 (0.43) | HSP90AB1ESRRGCA12CA1CA2 | |
| SCHEMBL3501242 | 0.78 | CES2 (0.43) | HSP90AB1ESRRGCA12CA1CA2 | |
| SCHEMBL177181 | 0.77 | HSP90AB1 (0.67) | HSP90AB1ESRRGCA12CA1CA2 | |
| SCHEMBL7760866 | 0.76 | CA12 (0.47) | HSP90AB1ESRRGCA12CA1CA2 | |
| SCHEMBL28472548 | 0.75 | CES2 (0.41) | ESRRGCA12CA1CA2CA7 | |
| SCHEMBL9440198 | 0.74 | HTT (0.44) | CA1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL9440247 | 0.74 | HTT (0.44) | CA1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL176969 | 0.74 | HTT (0.54) | HSP90AB1ESRRGCA12CA1CA2 | |
| SCHEMBL29799863 | 0.74 | MAOB (0.50) | HSP90AB1ESRRGCA12CA1CA2 | |
| SCHEMBL310878 | 0.74 | MAOB (0.50) | HSP90AB1ESRRGCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2484668-A1 | INDAZOLE ANALOGUE | Asahi Kasei Pharma Corporation (JP) | 2012-08-08 | — | — | EP | disclosed |