Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 8/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966754 | 0.94 | ADRB2 (0.46) | ADRB1ADRB3ADRB2DRD2DRD4 | |
| SCHEMBL966753 | 0.94 | ADRB2 (0.46) | ADRB1ADRB3ADRB2DRD2DRD4 | |
| SCHEMBL2054479 | 0.83 | ADRB2 (0.49) | ADRB1ADRB3ADRB2DRD2DRD4 | |
| SCHEMBL2054498 | 0.82 | MTNR1A (0.42) | MAPTL3MBTL1KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL965046 | 0.80 | ADRB2 (0.56) | ADRB1ADRB3ADRB2DRD2DRD4 | |
| SCHEMBL965047 | 0.80 | ADRB2 (0.56) | ADRB1ADRB3ADRB2DRD2DRD4 | |
| SCHEMBL965049 | 0.80 | ADRB2 (0.56) | ADRB1ADRB3ADRB2DRD2DRD4 | |
| SCHEMBL964403 | 0.80 | ADRB2 (0.57) | ADRB1ADRB3ADRB2DRD2DRD4 | |
| SCHEMBL964402 | 0.80 | ADRB2 (0.57) | ADRB1ADRB3ADRB2DRD2DRD4 | |
| SCHEMBL964401 | 0.80 | ADRB2 (0.57) | ADRB1ADRB3ADRB2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035004-B1 | PHENYL SUBSTITUTED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS POSSESSING BETA AGONIST ACTIVITY | PARION SCIENCES INC (US) | 2012-08-08 | — | — | EP | disclosed |