Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16921181 | 0.97 | TSHR (0.33) | TSHR | |
| SCHEMBL21907146 | 0.91 | TSHR (0.32) | TSHR | |
| SCHEMBL21905023 | 0.90 | TSHR (0.42) | TSHR | |
| SCHEMBL21905025 | 0.89 | — | — | |
| SCHEMBL11920359 | 0.89 | TSHR (0.40) | TSHR | |
| SCHEMBL15835252 | 0.89 | TSHR (0.31) | TSHR | |
| SCHEMBL11920351 | 0.89 | MTNR1A (0.36) | — | |
| SCHEMBL21905015 | 0.86 | CYP3A4 (0.38) | — | |
| SCHEMBL21163118 | 0.86 | MTNR1A (0.34) | — | |
| SCHEMBL14368845 | 0.85 | TSHR (0.47) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675783-B1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-04-22 | — | — | EP | disclosed |
| US-10370322-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-08-06 | — | — | US | disclosed |
| EP-3502092-A1 | ADDITION-FRAGMENTATION AGENTS | 3M Innovative Properties Company (US) | 2019-06-26 | — | — | EP | disclosed |
| US-20170210693-A1 | ADDITION-FRAGMENTATION AGENTS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2017-07-27 | — | — | US | disclosed |
| US-20170210693-A1 | ADDITION-FRAGMENTATION AGENTS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2017-07-27 | — | — | US | disclosed |
| US-9463146-B2 | Addition-fragmentation oligomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-10-11 | — | — | US | disclosed |
| US-20150328086-A1 | ADDITION-FRAGMENTATION OLIGOMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-11-19 | — | — | US | disclosed |
| US-20120208965-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-08-16 | — | — | US | disclosed |
| US-20120208965-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370322-B2 | Addition-fragmentation agents | NR4A1, PARP14, MTX1 | TSHR 1778/4885THRB 2735/4885PRKCA 4445/4885 |
| US-20150328086-A1 | ADDITION-FRAGMENTATION OLIGOMERS | FGB, ZYX, APBA1 | TSHR 4869/4885THRB 3557/4885PRKCA 4520/4885 |
| US-20120208965-A1 | ADDITION-FRAGMENTATION AGENTS | NR4A1, PARP14, MTX1 | TSHR 1778/4885THRB 2735/4885PRKCA 4445/4885 |
| US-20170210693-A1 | ADDITION-FRAGMENTATION AGENTS | NR4A1, PARP14, MTX1 | TSHR 1778/4885THRB 2735/4885PRKCA 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.