Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126322 | 0.98 | MAPT (0.81) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL5706144 | 0.93 | MAPT (0.68) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL13343243 | 0.92 | MAPT (0.71) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL141568 | 0.92 | MAPT (0.71) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL3424218 | 0.92 | MAPT (0.71) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2518984 | 0.92 | MAPT (0.67) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL12337501 | 0.92 | MAPT (0.71) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL12451790 | 0.91 | MAPT (0.69) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL12451793 | 0.91 | MAPT (0.69) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL14151751 | 0.91 | MAPT (0.69) | MAPTTDP1L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959873-B1 | GEL COMPOSITION AND METHODS | ALZA CORP (US) | 2006-03-01 | — | — | EP | claimed |
| US-5795695-A | PHOTO-QUALITY RECORDING | XEROX CORPORATION (US) | 1998-08-18 | — | — | US | claimed |
| US-4199517-A | DILVENTS, PLASTICIZERS AND IMPACT MODIFIERS | KENRICH PETROCHEMICALS, INC. (US) | 1980-04-22 | — | — | US | claimed |
| US-11179326-B2 | Short duration depot formulations | DURECT CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-10640688-B2 | Adhesive composition, protective film for a polarizing plate, polarizing plate, and liquid crystal display | LG CHEM, LTD. (KR) | 2020-05-05 | — | — | US | disclosed |
| US-20200129425-A1 | SHORT DURATION DEPOT FORMULATIONS | DURECT CORPORATION | 2020-04-30 | — | — | US | disclosed |
| US-10471001-B2 | Short duration depot formulations | DURECT CORPORATION (US) | 2019-11-12 | — | — | US | disclosed |
| US-10471002-B2 | Short duration depot formulations | DURECT CORPORATION (US) | 2019-11-12 | — | — | US | disclosed |
| US-20190269610-A1 | SHORT DURATION DEPOT FORMULATIONS | DURECT CORP (US) | 2019-09-05 | — | — | US | disclosed |
| US-20190183791-A1 | SHORT DURATION DEPOT FORMULATIONS | DURECT CORP (US) | 2019-06-20 | — | — | US | disclosed |
| US-10201496-B2 | Short duration depot formulations | DURECT CORPORATION (US) | 2019-02-12 | — | — | US | disclosed |
| US-5462993-A | Copolymer of acrylic esters, acrylonitrile, styrene half ester maleate soap, and curing agents for blending with polyvinyl chloride; heat and ultraviolet radiation resistance, artificial leather for automobile interiors | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0669370-A1 | Rubbery blend having low permanent compression set | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5415940-A | Multilayer panel for automobiles with rigid backing, semirigid urethane foams covered with polyvinyl chloride, plasticizer and rubber of addition polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| US-5380785-A | Leathery automotive material: polyvinyl chloride, plasticizer, rubbery polymer of butyl acrylate, at least one of methyl or ethyl /meth/acrylate, acrylonitrile, styrene, crosslinker, half ester maleate soap; emulsion polymerization, seed polymer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-01-10 | — | — | US | disclosed |
| US-5362787-A | Rubbery blend having low permanent compression set | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-11-08 | — | — | US | disclosed |
| EP-0619328-A1 | Rubbery polymer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-10-12 | — | — | EP | disclosed |
| US-4202810-A | USED AS ACCELERATORS, DILUENTS, PLASTICIZERS | KENRICH PETROCHEMICALS, INC. (US) | 1980-05-13 | — | — | US | disclosed |
| US-4199517-A | DILVENTS, PLASTICIZERS AND IMPACT MODIFIERS | KENRICH PETROCHEMICALS, INC. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4102862-A | Application of cumylphenol and derivatives thereof in plastic compositions | KENRICH PETROCHEMICALS, INC. (US) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10471001-B2 | Short duration depot formulations | VEGFA, MMP1, CD44 | MAPT 2866/4885TDP1 3211/4885L3MBTL1 2560/4885 |
| US-11179326-B2 | Short duration depot formulations | VEGFA, MMP1, CD44 | MAPT 2866/4885TDP1 3211/4885L3MBTL1 2560/4885 |
| US-20190183791-A1 | SHORT DURATION DEPOT FORMULATIONS | VEGFA, MMP1, CD44 | MAPT 2866/4885TDP1 3211/4885L3MBTL1 2560/4885 |
| US-10201496-B2 | Short duration depot formulations | VEGFA, MMP1, CD44 | MAPT 2866/4885TDP1 3211/4885L3MBTL1 2560/4885 |
| US-10471002-B2 | Short duration depot formulations | VEGFA, MMP1, CD44 | MAPT 2866/4885TDP1 3211/4885L3MBTL1 2560/4885 |
| US-20200129425-A1 | SHORT DURATION DEPOT FORMULATIONS | VEGFA, MMP1, CD44 | MAPT 2866/4885TDP1 3211/4885L3MBTL1 2560/4885 |
| US-20190269610-A1 | SHORT DURATION DEPOT FORMULATIONS | VEGFA, MMP1, CD44 | MAPT 2866/4885TDP1 3211/4885L3MBTL1 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.