SCHEMBL141568

SCHEMBL141568

COc1ccc(C(C)(C)c2ccc(OC(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.71
TDP1 Q9NUW8 2/20 0.71
L3MBTL1 Q9Y468 1/20 0.71
KMT2A Q03164 9/20 0.55
MEN1 O00255 3/20 0.55
LMNA P02545 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
ALDH1A1 P00352 2/20 0.54
PKM P14618 2/20 0.54
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
PARP10 Q53GL7 1/20 0.53
NPSR1 Q6W5P4 1/20 0.51
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
THRB P10828 1/20 0.50
CDK5 Q00535 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12451790 0.98 MAPT (0.69) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL2743136 0.96 MAPT (0.66) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL126322 0.94 MAPT (0.81) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL1192185 0.92 MAPT (0.78) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL13161708 0.89 MAPT (0.69) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL1546266 0.88 SMN1; SMN2 (0.68) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL13161715 0.88 MAPT (0.62) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL13161758 0.88 MAPT (0.71) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL141627 0.88 CA1 (0.66) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL12337501 0.88 MAPT (0.71) MAPTTDP1L3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170190907-A1 HIGH FLOW, HIGH HEAT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-06 US disclosed
US-9662833-B2 Marked thermoplastic compositions, methods of making and articles comprising the same, and uses thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-05-30 US disclosed
US-20170043530-A1 MARKED THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING AND ARTICLES COMPRISING THE SAME, AND USES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2017-02-16 US disclosed
US-20170037243-A1 HIGH HEAT POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-02-09 US disclosed
US-20170029618-A1 HIGH HEAT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-02-02 US disclosed
US-20170022360-A1 HIGH HEAT POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-01-26 US disclosed
US-20170022362-A1 HIGH HEAT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-01-26 US disclosed
US-20170022359-A1 HIGH HEAT POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-01-26 US disclosed
US-20170022361-A1 HIGH HEAT POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-01-26 US disclosed
US-9482969-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2016-11-01 US disclosed
US-7323536-B2 Reaction product obtained by melt blending an aromatic polyester-polycarbonate and a transesterification catalyst that has a haze of less than 5.0% GENERAL ELECTRIC COMPANY (US) 2008-01-29 US disclosed
US-7323535-B2 Reaction product obtained by melt blending an aromatic polyester-polycarbonate, a polycarbonate and a transesterification catalyst that has a haze of less than 1.0% GENERAL ELECTRIC COMPANY (US) 2008-01-29 US disclosed
US-20070273817-A1 Optical Compensator Film for Lcd Via Multilayer Structure LG CHEM, LTD. (KR) 2007-11-29 US disclosed
US-7183027-B2 Image forming method FUJI XEROX CO., LTD. (JP) 2007-02-27 US disclosed
US-7183027-B2 Image forming method FUJI XEROX CO., LTD. (JP) 2007-02-27 US disclosed
US-20070026334-A1 Electrophotographic photoreceptor and image forming apparatus including the same SHARP KABUSHIKI KAISHA (JP) 2007-02-01 US disclosed
US-20070027268-A1 Reaction product obtained by melt blending two aromatic polyester-polycarbonates and a transesterification catalyst that has a haze of less than 1.0% GENERAL ELECTRIC COMPANY (US) 2007-02-01 US disclosed
US-7160659-B2 Electrophotographic apparatus and process cartridge CANON KABUSHIKI KAISHA (JP) 2007-01-09 US disclosed
US-7160658-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2007-01-09 US disclosed
US-20070003853-A1 Image forming method, photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-04 US disclosed