SCHEMBL11921943

SCHEMBL11921943

CCCO[C@@H]1C(C)O[C@@H](O[C@@H]2C(COS(=O)(=O)O)O[C@@H](O[C@H]3C(C)O[C@@H](O[C@@H]4C(COS(=O)(=O)O)O[C@@H](O[C@H]5C(C)O[C@@H](O[C@@H]6C(COS(=O)(=O)O)O[C@@H](O[C@H]7C(C)O[C@@H](O[C@@H]8C(COS(=O)(=O)O)O[C@@H](OC)C(NSOOO)[C@H]8O)C(NSOOO)[C@@H]7O)C(NSOOO)[C@H]6O)C[C@@H]5O)C(NSOOO)[C@H]4O)C[C@@H]3O)C(NSOOO)[C@H]2O)C[C@@H]1O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 2/20 0.38
▸ BMP2 P12643 2/20 0.33
▸ VEGFA P15692 2/20 0.33
▸ CXCL12 P48061 2/20 0.33
▸ SHH Q15465 2/20 0.33
▸ FGF1 P05230 2/20 0.33
▸ HPSE Q9Y251 4/20 0.31
▸ PF4 P02776 2/20 0.31
▸ IFNG P01579 1/20 0.31
▸ CCL2 P13500 1/20 0.31
▸ SELP P16109 1/20 0.31
▸ BMP6 P22004 1/20 0.31
▸ CCL11 P51671 1/20 0.31
▸ WNT3A P56704 1/20 0.31
▸ SELPLG Q14242 1/20 0.31
▸ F2 P00734 1/20 0.30
▸ SERPINC1 P01008 1/20 0.30
▸ STAT3 P40763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11921952 0.90 F10 (0.42) F10FGF1HPSEF2SERPINC1
SCHEMBL11921951 0.87 F10 (0.41) F10FGF1HPSESERPINC1STAT3
SCHEMBL11921948 0.87 F10 (0.41) F10FGF1HPSESERPINC1STAT3
SCHEMBL11921953 0.87 F10 (0.41) F10FGF1HPSESERPINC1STAT3
SCHEMBL11921949 0.87 F10 (0.41) F10FGF1HPSESERPINC1STAT3
SCHEMBL11921950 0.87 F10 (0.41) F10FGF1HPSESERPINC1STAT3
SCHEMBL11921947 0.87 F10 (0.39) F10FGF1SERPINC1STAT3
SCHEMBL11921945 0.81 F10 (0.34) F10BMP2VEGFACXCL12SHH
SCHEMBL11921946 0.78 F10 (0.38) F10FGF1
SCHEMBL11997512 0.78 F10 (0.39) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9527930-B2 FGF receptor-activating N-sulfate oligosaccharides, preparation thereof, and therapeutic use thereof SANOFI (FR) 2016-12-27 — — US disclosed
US-20120202769-A1 FGF RECEPTOR-ACTIVATING N-SULFATE OLIGOSACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202769-A1 FGF RECEPTOR-ACTIVATING N-SULFATE OLIGOSACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF FGFR1, FGF1, FGF2 F10 225/4885BMP2 118/4885VEGFA 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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