SCHEMBL11921945

SCHEMBL11921945

CCCO[C@H]1CO[C@@H](O[C@@H]2C(COS(=O)(=O)O)O[C@@H](O[C@H]3CO[C@@H](O[C@@H]4C(COS(=O)(=O)O)O[C@@H](O[C@H]5CO[C@@H](OC)C[C@@H]5O)C(NSOOO)[C@H]4O)C[C@@H]3O)C(NSOOO)[C@H]2O)C[C@@H]1O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 1/20 0.34
▸ BMP2 P12643 1/20 0.30
▸ VEGFA P15692 1/20 0.30
▸ CXCL12 P48061 1/20 0.30
▸ SHH Q15465 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11997512 0.89 F10 (0.39) F10
SCHEMBL11921946 0.87 F10 (0.38) F10
SCHEMBL11921943 0.81 F10 (0.38) F10BMP2VEGFACXCL12SHH
SCHEMBL11921864 0.81 FGF1 (0.35) F10VEGFA
SCHEMBL11921947 0.78 F10 (0.39) F10
SCHEMBL11921952 0.76 F10 (0.42) F10
SCHEMBL11997499 0.74 F10 (0.40) F10BMP2VEGFACXCL12SHH
SCHEMBL11921953 0.74 F10 (0.41) F10
SCHEMBL11921951 0.74 F10 (0.41) F10
SCHEMBL11921949 0.74 F10 (0.41) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9527930-B2 FGF receptor-activating N-sulfate oligosaccharides, preparation thereof, and therapeutic use thereof SANOFI (FR) 2016-12-27 — — US disclosed
US-20120202769-A1 FGF RECEPTOR-ACTIVATING N-SULFATE OLIGOSACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202769-A1 FGF RECEPTOR-ACTIVATING N-SULFATE OLIGOSACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF FGFR1, FGF1, FGF2 F10 225/4885BMP2 118/4885VEGFA 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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