SCHEMBL11922017

SCHEMBL11922017

Cn1c2ccccc2c2ccc(N(c3ccccc3)c3ccc(-c4ccc(N(c5ccccc5)c5ccc6c7ccccc7n(C)c6c5)cc4)cc3)cc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
GPR3 P46089 1/20 0.50
KIF11 P52732 1/20 0.46
HPGD P15428 5/20 0.46
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 3/20 0.46
MAPT P10636 4/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
LMNA P02545 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PABPC1 P11940 1/20 0.43
ATM Q13315 1/20 0.42
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11922020 1.00 RXRA (0.51) RXRARXRBGPR3KIF11HPGD
SCHEMBL18564813 0.98 RXRA (0.50) RXRARXRBGPR3KIF11HPGD
SCHEMBL15747046 0.95 GPR3 (0.55) RXRARXRBGPR3KIF11HPGD
SCHEMBL11922037 0.94 RXRA (0.50) RXRARXRBGPR3KIF11HPGD
SCHEMBL11922021 0.94 RXRA (0.50) RXRARXRBGPR3KIF11HPGD
SCHEMBL11922034 0.94 RXRA (0.50) RXRARXRBGPR3KIF11HPGD
SCHEMBL18564663 0.94 RXRA (0.58) RXRARXRBGPR3KIF11HPGD
SCHEMBL18564662 0.94 RXRA (0.58) RXRARXRBGPR3KIF11HPGD
SCHEMBL18564880 0.93 RXRA (0.48) RXRARXRBGPR3KIF11HPGD
SCHEMBL11922028 0.93 GPR3 (0.46) RXRARXRBGPR3KIF11HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9650565-B2 Carbazole compound and use thereof TOSOH CORPORATION (JP) 2017-05-16 US disclosed
US-9650565-B2 Carbazole compound and use thereof TOSOH CORPORATION (JP) 2017-05-16 US disclosed
US-20170117486-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US disclosed
US-20170117486-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US disclosed
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2012-08-09 US disclosed
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2012-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF AR, DRD3, AHR RXRA 568/4885RXRB 589/4885GPR3 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.