Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178511 | 0.82 | TP53 (0.44) | USP2TP53NPC1RAB9ATSHR | |
| SCHEMBL14998867 | 0.81 | ALDH1A1 (0.57) | CASP1TP53NPC1RAB9ATSHR | |
| SCHEMBL11922867 | 0.79 | HPGD (0.47) | CASP1NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL10179851 | 0.78 | SCN1A (0.42) | USP2TP53TSHRALDH1A1MEN1 | |
| SCHEMBL10178641 | 0.77 | PLAU (0.51) | TP53NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL12630734 | 0.74 | CA1 (0.49) | TP53NPC1RAB9AALDH1A1OPRK1 | |
| SCHEMBL10001830 | 0.73 | TSHR (0.49) | NPC1RAB9ATSHRALDH1A1KMT2A | |
| SCHEMBL11922907 | 0.73 | ESR1 (0.43) | CASP1NPC1TSHRALDH1A1MEN1 | |
| SCHEMBL10178522 | 0.72 | SRD5A2 (0.56) | TP53NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL10178688 | 0.72 | SRD5A2 (0.56) | USP2RAB9ATSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202141-A1 | CHEMICAL AMPLIFICATION TYPE POSITIVE RESIST COMPOSITION, AND RESIST FILM, RESIST COATED MASK BLANKS AND RESIST PATTERN FORMING METHOD USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2012-08-09 | — | — | US | disclosed |