Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 16/20 | 0.72 |
| ▸ | CCNK | O75909 | 4/20 | 0.49 |
| ▸ | CDK9 | P50750 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466095 | 0.90 | CCNT1 (0.59) | CCNT1CCNKCDK9 | |
| SCHEMBL12465693 | 0.89 | CCNT1 (0.71) | CCNT1CCNKCDK9 | |
| SCHEMBL1191824 | 0.87 | CCNT1 (0.72) | CCNT1CCNKCDK9 | |
| SCHEMBL1225395 | 0.84 | CCNT1 (0.64) | CCNT1CCNKCDK9 | |
| SCHEMBL12850478 | 0.83 | CCNT1 (1.00) | CCNT1CCNKCDK9 | |
| SCHEMBL21747559 | 0.81 | CCNK (0.74) | CCNT1CCNKCDK9 | |
| SCHEMBL1193594 | 0.81 | CCNT1 (0.68) | CCNT1CCNKCDK9 | |
| SCHEMBL1225400 | 0.79 | CCNT1 (0.58) | CCNT1CCNKCDK9 | |
| SCHEMBL12898185 | 0.78 | CCNT1 (0.84) | CCNT1CCNKCDK9 | |
| SCHEMBL12466158 | 0.77 | CCNT1 (0.56) | CCNT1CCNKCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028492-A1 | Heteroaryl Compounds and Their Uses | NOVARTIS AG (CH) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028492-A1 | Heteroaryl Compounds and Their Uses | CDK9, CDK19, CDK3 | CCNT1 76/4885CCNK 39/4885CDK9 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.