SCHEMBL11928145

SCHEMBL11928145

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cn2nnc(C(C)(C)C)n2)nn1-c1ncccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 4/20 0.32
SLC2A3 P11169 4/20 0.32
SLC2A4 P14672 4/20 0.32
DHODH Q02127 2/20 0.32
SLC2A2 P11168 1/20 0.32
SLC16A3 O15427 2/20 0.32
SLC16A1 P53985 2/20 0.32
MCTS1 Q9ULC4 1/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PIN1 Q13526 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
ENPP2 Q13822 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2623667 0.94 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL11928376 0.94 SLC16A3 (0.33) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL798149 0.94 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL29454976 0.94 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL29454972 0.94 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL29454974 0.94 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL13085303 0.93 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL10083626 0.93 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL11928380 0.92 DHODH (0.34) DHODHSLC16A3SLC16A1ALDH1A1SMN1; SMN2
SCHEMBL11928142 0.91 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4DHODHSLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484676-B1 Tetrazol-substituted anthranilic acid amides as pesticides BAYER CROPSCIENCE AG (DE) 2015-01-21 EP disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
EP-2484676-A2 Tetrazol-substituted anthranilic acid amides as pesticides Bayer CropScience AG (DE) 2012-08-08 EP disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SLC2A1 2324/4885SLC2A3 2023/4885SLC2A4 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.