Mip-1095

Mip-1095

SCHEMBL11930755

O=C(O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)Nc1ccc(I)cc1)C(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mip-1095 I-123 SCHEMBL17558049 1.00 FOLH1 (1.00) FOLH1
Mip-1095 I-123 SCHEMBL4326617 1.00 FOLH1 (1.00) FOLH1
SCHEMBL24354421 0.95 FOLH1 (0.91) FOLH1
SCHEMBL16654681 0.95 FOLH1 (0.91) FOLH1
SCHEMBL4326624 0.95 FOLH1 (0.91) FOLH1
SCHEMBL11977615 0.92 FOLH1 (0.84) FOLH1
SCHEMBL11977608 0.92 FOLH1 (0.84) FOLH1
SCHEMBL13287695 0.91 FOLH1 (0.83) FOLH1
SCHEMBL23077794 0.91 FOLH1 (0.82) FOLH1
SCHEMBL11977601 0.89 FOLH1 (1.00) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099626-A1 METHODS AND SYSTEMS FOR MANUFACTURING RADIOPHARMACEUTICALS NOVARTIS AG (CH) 2026-05-15 — — WO claimed
WO-2026088112-A1 COMBINATION THERAPIES WITH AR-DEGRADING AGENTS AND PSMA-TARGETING RADIOLIGANDS NOVARTIS AG (CH) 2026-04-30 — — WO claimed
EP-4554621-A1 COMBINED THERAPY WITH NANOPARTICLES AND RADIOPHARMACEUTICALS UNIVERSITE DE MONTPELLIER (FR) 2025-05-21 — — EP claimed
US-20250064948-A1 GCPII INHIBITION FOR THE TREATMENT OF SARCOPENIA AND AGING THE JOHNS HOPKINS UNIVERSITY 2025-02-27 — — US claimed
WO-2025038942-A1 PROSTATE-SPECIFIC MEMBRANE ANTIGEN AS AN IMAGING BIOMARKER IN INFLAMMATORY BOWEL DISEASE THE JOHNS HOPKINS UNIVERSITY (US) 2025-02-20 — — WO claimed
CN-110730908-B Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified versions thereof and related methods 朱诺治疗学股份有限公司 2025-01-21 — — CN claimed
WO-2024013272-A1 COMBINED THERAPY WITH NANOPARTICLES AND RADIOPHARMACEUTICALS UNIVERSITE DE MONTPELLIER (FR) 2024-01-18 — — WO claimed
US-20230364271-A1 METHODS AND COMPOSITIONS FOR INCREASING UPTAKE, INTERNALIZATION, AND/OR RETENTION OF SMALL MOLECULE LIGANDS CORNELL UNIVERSITY 2023-11-16 — — US claimed
WO-2023154939-A2 GCPII INHIBITION FOR THE TREATMENT OF SARCOPENIA AND AGING THE JOHNS HOPKINS UNIVERSITY (US) 2023-08-17 — — WO claimed
EP-4221763-A1 METHODS AND COMPOSITIONS FOR INCREASING UPTAKE, INTERNALIZATION, AND/OR RETENTION OF SMALL MOLECULE LIGANDS Cornell University (US) 2023-08-09 — — EP claimed
US-20230190796-A1 ENGINEERED CELLS EXPRESSING PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) OR A MODIFIED FORM THEREOF AND RELATED METHODS JUNO THERAPEUTICS, INC. (US) 2023-06-22 — — US claimed
US-20220202950-A1 COMPOSITIONS COMPRISING BACTERIALLY DERIVED INTACT MINICELLS FOR THERANOSTIC APPLICATIONS ENGENEIC MOLECULAR DELIVERY PTY LTD (AU) 2022-06-30 — — US claimed
WO-2022072292-A1 METHODS AND COMPOSITIONS FOR INCREASING UPTAKE, INTERNALIZATION, AND/OR RETENTION OF SMALL MOLECULE LIGANDS CORNELL UNIVERSITY (US) 2022-04-07 — — WO claimed
EP-4746926-A2 PSMA-TARGETING RADIOLIGAND TREATMENT REGIMEN Novartis AG (CH) 2026-05-27 — — EP disclosed
EP-4743125-A1 METHOD OF TREATING PROSTATE CANCER Novartis AG (CH) 2026-05-20 — — EP disclosed
WO-2026099626-A1 METHODS AND SYSTEMS FOR MANUFACTURING RADIOPHARMACEUTICALS NOVARTIS AG (CH) 2026-05-15 — — WO disclosed
US-20100178246-A1 TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES AND METHODS OF USE THEREOF FOR INHIBITING PSMA MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2010-07-15 — — US disclosed
US-20080193381-A1 HETERODIMERS OF GLUTAMIC ACID MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2008-08-14 — — US disclosed
US-20080193381-A1 HETERODIMERS OF GLUTAMIC ACID MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2008-08-14 — — US disclosed
WO-2008058192-A2 HETERODIMERS OF GLUTAMIC ACID MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2008-05-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100178246-A1 TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES AND METHODS OF USE THEREOF FOR INHIBITING PSMA PSMA1, PSMA5, PSMA3 FOLH1 4/4885
US-20080193381-A1 HETERODIMERS OF GLUTAMIC ACID DDO, GLUL, ASNS FOLH1 5/4885
US-20250064948-A1 GCPII INHIBITION FOR THE TREATMENT OF SARCOPENIA AND AGING DGKI, PGC, MPC2 FOLH1 149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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