SCHEMBL1193322

SCHEMBL1193322

CCCCC(C)(C)N(Sc1nc2ccccc2s1)C(C)CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.44
ALDH1A1 P00352 5/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
KDM4E B2RXH2 2/20 0.42
GFER P55789 1/20 0.42
CYP1A2 P05177 4/20 0.42
CYP2D6 P10635 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C19 P33261 2/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42
HTR1A P08908 1/20 0.41
HTR2A P28223 1/20 0.41
HTR7 P34969 1/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 2/20 0.41
ADRA2A P08913 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
DRD2 P14416 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1194511 0.92 FBP1 (0.45) FBP1ALDH1A1SMN1; SMN2KDM4EGFER
SCHEMBL1419664 0.88 FBP1 (0.48) FBP1ALDH1A1SMN1; SMN2KDM4EGFER
SCHEMBL1194268 0.85 FBP1 (0.50) FBP1ALDH1A1SMN1; SMN2KDM4EGFER
SCHEMBL1194363 0.84 FBP1 (0.47) FBP1ALDH1A1SMN1; SMN2KDM4EGFER
SCHEMBL1193987 0.83 ALDH1A1 (0.48) FBP1ALDH1A1SMN1; SMN2KDM4EGFER
SCHEMBL1193640 0.82 FBP1 (0.47) FBP1ALDH1A1SMN1; SMN2KDM4EGFER
SCHEMBL1194310 0.81 SMN1; SMN2 (0.46) FBP1ALDH1A1SMN1; SMN2KDM4EGFER
SCHEMBL1193452 0.81 ALDH1A1 (0.46) FBP1ALDH1A1SMN1; SMN2KDM4EGFER
SCHEMBL9702325 0.81 FBP1 (0.48) FBP1ALDH1A1SMN1; SMN2KDM4EGFER
SCHEMBL1419324 0.79 FBP1 (0.49) FBP1ALDH1A1SMN1; SMN2KDM4EGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8796387-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2014-08-05 US disclosed
US-8609252-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2013-12-17 US disclosed
EP-2233521-B1 RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2013-09-04 EP disclosed
EP-2316879-B1 RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2013-08-07 EP disclosed
US-20110184109-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-28 US disclosed
US-20110172339-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-14 US disclosed
US-20110166277-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-07 US disclosed
US-20110124787-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-05-26 US disclosed
US-20110118397-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-05-19 US disclosed
EP-2316881-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed
EP-2316879-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed
EP-2316880-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed
EP-2301997-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-03-30 EP disclosed
EP-2298834-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-03-23 EP disclosed
US-20110034638-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-02-10 US disclosed
EP-2233521-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2010-09-29 EP disclosed