Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | MITF | O75030 | 2/20 | 0.76 |
| ▸ | XBP1 | P17861 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.73 |
| ▸ | HTT | P42858 | 6/20 | 0.73 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | RNF4 | P78317 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503954 | 0.91 | NPC1 (0.66) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL2635734 | 0.91 | NPC1 (0.66) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL16922181 | 0.91 | NPC1 (0.66) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL916728 | 0.89 | POLB (0.73) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL7800005 | 0.89 | NPC1 (0.63) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL1193345 | 0.89 | NPC1 (0.63) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL1707504 | 0.89 | RAB9A (0.63) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL2320435 | 0.89 | NPC1 (0.63) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL5903996 | 0.89 | ALDH1A1 (0.67) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL11128513 | 0.89 | NPC1 (0.63) | NPC1RAB9AMITFXBP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |
| WO-1996026922-A1 | NOVEL SULPHONAMIDE BI-TRYPTAMINE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE OF SAID DERIVATIVES AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-09-06 | — | — | WO | disclosed |
| WO-1996026923-A1 | NOVEL BI-TRYPTAMINIC DERIVATIVES, PREPARATION PROCESS AND UTILIZATION AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-09-06 | — | — | WO | disclosed |