Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.86 |
| ▸ | HPGD | P15428 | 7/20 | 0.86 |
| ▸ | CA1 | P00915 | 2/20 | 0.86 |
| ▸ | CA9 | Q16790 | 2/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.86 |
| ▸ | CA12 | O43570 | 1/20 | 0.86 |
| ▸ | CA2 | P00918 | 1/20 | 0.86 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.86 |
| ▸ | CA4 | P22748 | 1/20 | 0.86 |
| ▸ | CA6 | P23280 | 1/20 | 0.86 |
| ▸ | CA7 | P43166 | 1/20 | 0.86 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.86 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CASP7 | P55210 | 2/20 | 0.59 |
| ▸ | G6PD | P11413 | 1/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL1810677 | 0.95 | ALDH1A1 (0.86) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL28189123 | 0.93 | ALDH1A1 (0.82) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL29110644 | 0.93 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL27499117 | 0.93 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL29606432 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL29362663 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL17156443 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL29360246 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL8433746 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL1967 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDCA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110186381-A1 | SOUND ABSORBING MATERIAL, MULTILAYER SOUND ABSORBING MATERIAL, MOLDED PRODUCT OF MULTILAYER SOUND ABSORBING MATERIAL, SOUND ABSORBING INTERIOR MATERIAL, AND SOUND ABSORBING FLOOR COVERING MATERIAL | NAGOYA OILCHEMICAL CO., LTD (JP) | 2011-08-04 | — | — | US | disclosed |
| EP-2333766-A1 | SOUND ABSORBING MATERIAL, MULTILAYER SOUND ABSORBING MATERIAL, MOLDED PRODUCT OF MULTILAYER SOUND ABSORBING MATERIAL, SOUND ABSORBING INTERIOR MATERIAL, AND SOUND ABSORBING FLOOR COVERING MATERIAL | Nagoya Oil Chemical Co., Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-20110108359-A1 | IMPACT AND SOUND ABSORBING MATERIAL AND SOUND ABSORBING STRUCTURE | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2011-05-12 | — | — | US | disclosed |
| EP-2302620-A1 | IMPACT AND SOUND ABSORBING MATERIAL AND SOUND ABSORBING STRUCTURE | Toyota Jidosha Kabushiki Kaisha (JP) | 2011-03-30 | — | — | EP | disclosed |
| US-20110027534-A1 | MOLD RELEASE SHEET AND MOLDED ARTICLES | NAGOYA OILCHEMICAL CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
| EP-0984031-B1 | MOLDING MATERIAL, INNER MATERIAL USING THE SAME, AND METHOD FOR PRODUCING THE SAME | NAGOYA OILCHEMICAL (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0984031-A1 | MOLDING MATERIAL, INNER MATERIAL USING THE SAME, AND METHOD FOR PRODUCING THE SAME | Nagoya Oilchemical Co., Ltd. (JP) | 2000-03-08 | — | — | EP | disclosed |