Salicylic Acid

Salicylic Acid

SCHEMBL8433746

O=C(O)c1ccccc1O.OO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
KDM4E B2RXH2 6/20 1.00
HPGD P15428 6/20 1.00
CA12 O43570 3/20 1.00
CA1 P00915 3/20 1.00
CA2 P00918 3/20 1.00
CA7 P43166 3/20 1.00
CA9 Q16790 3/20 1.00
CA14 Q9ULX7 3/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
HMGB1 P09429 1/20 1.00
CA4 P22748 1/20 1.00
CA6 P23280 1/20 1.00
NAPRT Q6XQN6 1/20 1.00
ALOX15 P16050 2/20 0.68
HSD17B10 Q99714 4/20 0.61
MAPT P10636 2/20 0.61
TSHR P16473 2/20 0.61
G6PD P11413 1/20 0.60
CASP7 P55210 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL17156443 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDCA12CA1
Salicylic Acid SCHEMBL29360246 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDCA12CA1
Salicylic Acid SCHEMBL29606432 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDCA12CA1
Salicylic Acid SCHEMBL1509155 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDCA12CA1
Salicylic Acid SCHEMBL1967 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDCA12CA1
Salicylic Acid SCHEMBL29362663 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDCA12CA1
Salicylic Acid SCHEMBL9982 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDCA12CA1
Salicylic Acid SCHEMBL299754 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDCA12CA1
Salicylic Acid SCHEMBL546853 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDCA12CA1
Salicylic Acid SCHEMBL12477692 0.97 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0958405-A1 METAL SURFACE TREATMENT SOLUTIONS AND PROCESS SOLVAY INTEROX LIMITED (GB) 1999-11-24 EP disclosed
WO-1998015674-A1 METAL SURFACE TREATMENT SOLUTIONS AND PROCESS SOLVAY INTEROX LIMITED (GB) 1998-04-16 WO disclosed