SCHEMBL11937129

SCHEMBL11937129

O=C(Oc1ccc(N2C(=O)C=CC2=O)cc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.54
ACR P10323 1/20 0.54
HSP90AA1 P07900 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
HTT P42858 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
CACNA1B Q00975 1/20 0.50
APBA1 Q02410 1/20 0.50
KMT2A Q03164 2/20 0.48
DDAH1 O94760 1/20 0.47
SRD5A1 P18405 1/20 0.46
SRD5A2 P31213 1/20 0.46
PKM P14618 2/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
CCR6 P51684 1/20 0.44
ATM Q13315 1/20 0.44
MGLL Q99685 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18434903 0.91 PRSS1 (0.49) PRSS1ACRHSP90AA1TDP1ALDH1A1
SCHEMBL12268600 0.88 HSP90AA1 (0.61) PRSS1HSP90AA1TDP1ALDH1A1HPGD
SCHEMBL20938446 0.88 HSP90AA1 (0.61) PRSS1HSP90AA1TDP1ALDH1A1HPGD
SCHEMBL12268812 0.86 TDP1 (0.54) PRSS1ACRHSP90AA1TDP1ALDH1A1
SCHEMBL20938433 0.84 HSP90AA1 (0.56) PRSS1HSP90AA1TDP1ALDH1A1HPGD
SCHEMBL20989702 0.84 HSP90AA1 (0.56) PRSS1HSP90AA1TDP1ALDH1A1HPGD
SCHEMBL12268715 0.84 HSP90AA1 (0.56) PRSS1HSP90AA1TDP1ALDH1A1HPGD
SCHEMBL9682438 0.83 PRSS1 (0.71) PRSS1ACRTDP1KMT2ASRD5A2
SCHEMBL28639038 0.83 PRSS1 (0.71) PRSS1ACRTDP1KMT2ASRD5A2
SCHEMBL13839733 0.81 HSP90AA1 (0.54) PRSS1HSP90AA1TDP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9785011-B2 Liquid crystal display having improved wavelength dispersion characteristics AKRON POLYMER SYSTEMS (US) 2017-10-10 US disclosed
US-9785011-B2 Liquid crystal display having improved wavelength dispersion characteristics AKRON POLYMER SYSTEMS (US) 2017-10-10 US disclosed
EP-2706402-B1 Optical compensation films based on stretched polymer films AKRON POLYMER SYSTEMS (US) 2017-02-01 EP disclosed
US-9096719-B2 Optical compensation films with mesogen groups for liquid crystal display AKRON POLYMER SYSTEMS (US) 2015-08-04 US disclosed
US-9096719-B2 Optical compensation films with mesogen groups for liquid crystal display AKRON POLYMER SYSTEMS (US) 2015-08-04 US disclosed
US-9011992-B2 Optical compensation films based on stretched polymer films AKRON POLYMER SYSTEMS (US) 2015-04-21 US disclosed
US-9011992-B2 Optical compensation films based on stretched polymer films AKRON POLYMER SYSTEMS (US) 2015-04-21 US disclosed
US-8821994-B2 Liquid crystal display having improved wavelength dispersion characteristics AKRON POLYMER SYSTEMS (US) 2014-09-02 US disclosed
US-8821994-B2 Liquid crystal display having improved wavelength dispersion characteristics AKRON POLYMER SYSTEMS (US) 2014-09-02 US disclosed
US-20140211311-A1 LIQUID CRYSTAL DISPLAY HAVING IMPROVED WAVELENGTH DISPERSION CHARACTERISTICS AKRON POLYMER SYSTEMS (US) 2014-07-31 US disclosed
US-20080241427-A1 Optical retardation compensation film having positive C-plate and at least one negative C-plate; LCD device; optical switches and waveguides AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080241427-A1 Optical retardation compensation film having positive C-plate and at least one negative C-plate; LCD device; optical switches and waveguides AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080241428-A1 Optical compensation films with disk groups for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080239491-A1 Optical compensation films having positive birefringence for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080241428-A1 Optical compensation films with disk groups for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080239491-A1 Optical compensation films having positive birefringence for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080241565-A1 Optical compensation films with birefringence enhancing substituents for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080241565-A1 Optical compensation films with birefringence enhancing substituents for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080237552-A1 Optical compensation films with mesogen groups for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080237552-A1 Optical compensation films with mesogen groups for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed