Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.71 |
| ▸ | ACR | P10323 | 3/20 | 0.71 |
| ▸ | KIF11 | P52732 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639038 | 1.00 | PRSS1 (0.71) | PRSS1ACRKIF11CES2CES1 | |
| SCHEMBL28641893 | 0.93 | PRSS1 (0.64) | PRSS1ACRKIF11CES2CES1 | |
| SCHEMBL8074121 | 0.93 | PRSS1 (0.64) | PRSS1ACRKIF11CES2CES1 | |
| SCHEMBL14640734 | 0.93 | PRSS1 (0.64) | PRSS1ACRKIF11CES2CES1 | |
| SCHEMBL14640390 | 0.93 | PRSS1 (0.64) | PRSS1ACRKIF11CES2CES1 | |
| SCHEMBL8072562 | 0.91 | LMNA (0.63) | PRSS1ACRKIF11MAPTTDP1 | |
| SCHEMBL8058452 | 0.91 | LMNA (0.63) | PRSS1ACRKIF11MAPTTDP1 | |
| SCHEMBL30576748 | 0.91 | PRSS1 (0.71) | PRSS1ACRKIF11CES2CES1 | |
| SCHEMBL21771902 | 0.91 | MAPT (0.71) | PRSS1ACRKIF11CES2CES1 | |
| SCHEMBL11059672 | 0.91 | PRSS1 (0.62) | PRSS1ACRKIF11CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |