Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11938254 | 0.92 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1SMN1; SMN2POLB | |
| SCHEMBL13915151 | 0.84 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL13915083 | 0.84 | MEN1 (0.37) | ALDH1A1TSHRMAPK1SMN1; SMN2POLB | |
| SCHEMBL2777997 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPK1SMN1; SMN2POLB | |
| SCHEMBL24243983 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1TSHRMAPK1SMN1; SMN2POLB | |
| SCHEMBL15062363 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1TSHRMAPK1SMN1; SMN2POLB | |
| SCHEMBL3230281 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1TSHRMAPK1SMN1; SMN2POLB | |
| SCHEMBL3219761 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1TSHRMAPK1SMN1; SMN2POLB | |
| SCHEMBL14980570 | 0.81 | MEN1 (0.39) | ALDH1A1TSHRSMN1; SMN2POLBMEN1 | |
| SCHEMBL13915152 | 0.78 | PAOX (0.38) | ALDH1A1TSHRMAPK1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227610-B2 | Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques | CARNEGIE MELLON UNIVERSITY (US) | 2012-07-24 | — | — | US | disclosed |
| US-20090074673-A1 | Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques | CARNEGIE MELLON UNIVERSITY (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090074673-A1 | Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques | NES, MKI67, CD68 | ALDH1A1 4063/4885TSHR 3981/4885MAPK1 2374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.