SCHEMBL11938345

SCHEMBL11938345

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nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.49
▸ MAPT P10636 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ POLB P06746 1/20 0.47
▸ CTDSP1 Q9GZU7 1/20 0.47
▸ STAT3 P40763 17/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30819230 0.93 MAPT (0.58) MEN1MAPTKMT2APOLBCTDSP1
SCHEMBL31179894 0.84 POLB (0.54) MEN1MAPTKMT2APOLBCTDSP1
SCHEMBL29426138 0.76 MAPT (0.57) MEN1MAPTKMT2APOLBCTDSP1
SCHEMBL29425813 0.74 POLB (0.59) MEN1MAPTKMT2APOLBCTDSP1
Phloyoside I SCHEMBL29426051 0.69 POLB (0.55) MEN1MAPTKMT2APOLBCTDSP1
Phlomiol SCHEMBL9057941 0.69 POLB (0.55) MEN1MAPTKMT2APOLBCTDSP1
SCHEMBL20476536 0.68 POLB (0.52) MEN1MAPTKMT2APOLBCTDSP1
SCHEMBL31179905 0.67 POLB (0.51) MEN1MAPTKMT2APOLBCTDSP1
SCHEMBL30782246 0.67 POLB (0.51) MEN1MAPTKMT2APOLBCTDSP1
SCHEMBL29426020 0.67 POLB (0.51) MEN1MAPTKMT2APOLBCTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8227426-B2 Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care ISLAND KINETICS INC. (US) 2012-07-24 — — US disclosed
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care ISLAND KINETICS INC. (US) 2011-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care GLA, LPO, PLOD3 MEN1 2856/4885MAPT 2800/4885KMT2A 3121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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